Kambo Peptides

As of now, there has been little research done on Kambo as a holistic treatment. However, there has been some research into isolated peptides from the secretions starting in the 1980’s, by scientist Vittorio Erspamer of the University of Rome. He was nominated twice for the Nobel Prize and is considered to be the first scientist to analyze Kambo in the laboratory concluding that Kambo contains a “fantastic chemical cocktail with potential medical applications unmatched by any other amphibian.” Kambo has the ability to cross the blood-brain barrier, which means it can penetrate deep into the cells and where it can draw out toxins and free radicals. Thus far, researchers have discovered 9 different peptides (a short chain of amino acids), some of which are bio-active- triggering inherent physiological programs in the human body which activate different self-healing mechanisms.

The research conducted has shown the chemical makeup of Kambo to contain short chains of amino acids, known as peptides, that affect gastrointestinal muscles and blood circulation as well as stimulate the adrenal cortex and pituitary gland in the brain. While there are no clinical studies that definitively back up Kambo’s efficacy, the properties of Kambo peptides suggest it may be a promising treatment for the multiple conditions:

As a testament to their medicinal properties, there are now over 70 Kambo related patents lodged. As with venoms from snakes and scorpions, researchers believe that Kambo will open up a new world of treatments for Chronic Fatigue Syndrome, Chronic Pain, Cancer, HIV, Parkinson’s Disease, Alzheimer’s, Depression, Vascular problems, Hepatitis, Diabetes, Rheumatism, Arthritis, Addictions and much, much more.

Please keep in mind that these are not medical claims. The field of science is rapidly changing, and I encourage you to do your own research.

Peptides

Phyllomedusin

(Tachykinins Family) – A neuropeptide with powerful vasodialator effects. Produces contraction at the smooth muscle level, and increase secretions of the entire gastrointestinal tract (such as the salivary glands, stomach, small and large intestine, pancreas and gallbladder). These working with Phyllokinin are the main peptides responsible for the deep purge produced when receiving Kambo.

Phyllokinin

(Bradykinins Family) – Potent vasodilator. Important peptide of scientific study as they are hypotensive, and increase vascular permeability (due to contraction of the non-vascular smooth muscle). Increasing the permeability of the blood-brain barrier is a min focus of scientific study. Phyllokinin is also related to the mechanism of inflammatory pain, and also possesses antimicrobial and antifungal properties.

Phylloaerulein

(Caeruleins Family)– Neuropeptides with chains of 40 amino acids which produce strong contractions of the smooth muscle tissue. They contribute to a drop in blood pressure, modifying satiety and the body’s thermoregulation. They stimulate the adrenal cortex and pituitary gland, contributing to greater sensory perception. These peptides also possess great analgesic (pain relieving) properties. It is these peptides that are largely responsible for the sensations of nausea, vomiting, palpations and sweating during a Kambo treatment.

Dermorphin

(Sauvagine Family) – These heptapeptides produce a powerful opiate-like activity on mu-type opioid receptors and have a potent analgesic effect that is 30-40 times more potent than Morphine. Dermorphin may also have effects on pulmonary ventilation and pituitary hormone release.

Deltorphin

(Deltorphin Family) – These small peptides are composed of 7 amino acids. They are selective agonists of the opiate delta receptors being 4000 times more potent than morphine and 40 times more than the endogenous endorphins.

Dermaseptin & Adenoregulin (B2)

(Dermaseptin Family) – These antimicrobial peptides are involved in the defense of the frog’s bare skin against microbial invasion. They also show lethal effects against a broad spectrum of bacteria, fungi, yeasts and protozoa. Several years of research carried out at the University of Paris have shown that peptides Dermaseptin and Dermaseptin B2 are effective in killing certain types of cancer cells. Researchers at Queens University (Belfast) won a prestigious award for their ground-breaking work with cancer and Kambo. Dermaseptin B2 operates in the body through the adenosine receptors (a fundamental component throughout all human cellular fuel). These receptors may offer a target for the treatment of depression, stroke; and cognitive loss diseases, such as Alzheimer’s and Parkinson’s.

Phyllolitorin / Rohdei-Litorin

(Bombesins Family)-These are neuropeptides that are active in the central and peripheral nervous system. They stimulate the secretion of hydrochloric acid by acting on the G cells of the stomach. They also increase pancreatic secretion and smooth muscle contractibility.

Tryptophilins

These neuropeptides consist of 4 to 14 amino acids, which are opening up new perspectives on how the human brain works. These have also been found to be highly potent against opportunistic infections such as HIV, bacteria, fungi, protozoa and yeast, including Candida Albicans.